If you are a Type 2 diabetic, you may be familiar with the prescription drug, Actos, which is also marketed under different names such as Glustin, Glizone, Pioz and Zactos. The drug is widely distributed in the USA, the UK, Canada, Germany, Europe, India and Mexico and is also known as the tenth-best selling drug in America with sales exceeding two billion dollars. At the height of its popularity, Actos was hailed as the improved version of Avandia, another drug medicine found to increase the risk of congestive heart failure in diabetic patients.
Actos, medically known as pioglitazone, reduces insulin resistance in the patient’s peripheral tissues and liver while also increasing the outflow of insulin-dependent glucose. By doing this, the drug can effectively slow down the extraction of glucose from the liver, which then lowers the amount of glucose and glycated hemoglobin in the patient’s bloodstream. While most patients report a decrease in their blood sugar levels after two weeks, it should be noted that Actos can control Type 2 diabetes, but it cannot cure this condition.
Besides treating patients with mellitus type 2 diabetes, pioglitazone has also been used to treat fatty liver disorders and pre-diabetic patients. The drug was believed to be so effective that it could reduce the probability of pre-diabetic patients developing diabetes mellitus type 2 by over 70%.
The problem with the drug is that pioglitazone can not be taken by those with hypersensitivity to any ingredients contained in the drug. Furthermore, the fact that Actos is safe for pregnancy, lactating mothers and those under 18 was also never properly established. What has become clear is that those suffering from acute disease of the liver as well as those prone to heart failure can suffer mortal consequences should they choose to treat their condition with Actos.
Just like any other drug in the thiazolidinedione group, Actos is also believed to increase the patient’s chances of developing congestive heart failure, which occurs when the heart is simply too weak to pump sufficient blood to other parts of the body. This means that diabetic patients with severe heart condition, swelling of limbs, high cholesterol, high blood pressure, narrow blood vessels, irregular heartbeats, or sleep apnea, and heart attack survivors, should all be discouraged from taking this drug.
At this point of writing, Actos has been officially banned by both the French Agency for the Safety of Health Products and Germany’s Federal Institute for Drugs and Medical Devices pending investigation of the drug’s association with the formation of bladder tumors. As this prescription alters blood sugar levels, patients taking it may also suffer from sudden low or high blood sugar levels, resulting in:
While the above side effects are not detrimental to one’s long term health, other dangerous side effects may include:
While these side effects can certainly impact the quality of your life, medical results have also found that Actos can cause irreversible liver problems. These side effects include:
Besides dramatically increasing one’s chances of suffering from liver failure, diabetic patients who have taken Actos are also much more likely to develop bladder cancer after one year of treatment. Women who took the prescription drug have also reported a higher increase in bone fracture along the upper arms, hands and feet.
In the event that you tragically develop congestive heart failure while on Actos medication, you may develop certain symptoms such as:
Despite the many FDA warnings attached to the product, Actos remains a best-selling prescription drug for type 2 diabetics around the world. If you or a loved one has suffered due to the ingestion of Actos, contact trial lawyer Bruce Hagen, as he can help Actos victims seek substantial recovery via a class action suit against Takeda Pharmaceuticals, producers of the Actos drug.
Bruce Hagen is an experienced Georgia trial attorney who can provide you with the best options and legal advice on how you can pursue a claim if you believe you were injured by Actos. Contact our law firm today to talk more about your situation and the options for an Actos class action claim available to you.